DRUG LOADED POLYMERIC NANOPARTICLES AND METHODS OF MAKING AND USING THE SAME

摘要

PROBLEM TO BE SOLVED: To provide nanoparticle therapeutics and methods of making such nanoparticles that are capable of delivering therapeutic levels of drugs to treat diseases such as cancer while also reducing patient side effects.SOLUTION: Therapeutic nanoparticles contain: about 0.2 to about 35 weight percent of a therapeutic agent; about 10 to about 99 weight percent of a diblock poly(lactic) acid-poly(ethylene)glycol copolymer or diblock poly(lactic)-co-poly(glycolic) acid-poly(ethylene)glycol copolymer; and about 0 to about 75 weight percent of poly(lactic) acid or poly(lactic) acid-co-poly(glycolic) acid.SELECTED DRAWING: None