发明名称 |
Alphavirus replicon particles encoding IL- 12 as immunological adjuvants |
摘要 |
<p>The immune response to an antigen of interest, either in purified form or expressed via an alphavirus replicon particle, can be enhanced by the simultaneous administration of an alphavirus replicon particle which expresses interleukin-12. This allows for the use of significantly smaller quantities of the antigen and this immunization strategy can also eliminate the need for boosting administration of the antigen or it can reduce the number of boosts required for an effective immune response to the antigen.</p> |
申请公布号 |
AU2007342333(A1) |
申请公布日期 |
2008.07.17 |
申请号 |
AU20070342333 |
申请日期 |
2007.09.12 |
申请人 |
ALPHAVAX, INC. |
发明人 |
LAURA COPP;BOLYN HUBBY;PETER BERGLUND;JONATHAN F. SMITH;WHITNEY ELLIS |
分类号 |
A61K39/145;A61K35/76;C07K14/18 |
主分类号 |
A61K39/145 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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