发明名称 |
SHORT PEPTIDES DERIVED FROM VDAC1, COMPOSITIONS AND METHODS OF USE THEREOF |
摘要 |
The present invention relates to short peptides based on the amino acids sequence of the N-terminal domain of the human mitochondrial protein voltage-dependent anion channel 1 (VDAC) and to peptide conjugates having a cell permeability enhancing moiety. The peptides, peptide conjugates and pharmaceutical compositions containing them are useful for treating diseases characterized by cell hyperproliferation or resistance to cell death and in particular, cancer. |
申请公布号 |
US2016176937(A1) |
申请公布日期 |
2016.06.23 |
申请号 |
US201414907445 |
申请日期 |
2014.07.24 |
申请人 |
B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN GURION UNIVERSITY |
发明人 |
SHOSHAN-BARMATZ Varda |
分类号 |
C07K14/47;C07K14/435 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Beer-Sheva IL |