THERAPEUTIC COMPOUNDS AND USES THEREOF

摘要

Described herein are compounds of Formula (I)-(III), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Also provided are particles (e.g., nanoparticles) comprising compounds of Formula (I)-(III) and pharmaceutical compositions thereof that are mucus penetrating. Methods of using the compounds or pharmaceutical compositions thereof for treating and/or preventing diseases are also provided.;

主权项

1. A compound of Formula (I): or a pharmaceutically acceptable salt thereof, wherein:
R1 is H or optionally substituted C1-6 alkyl;R2 is optionally substituted bicyclic heterocyclyl having 1 or 2 heteroatoms;X is a bond, —O—, or —C(═O)—;Y is CH;R3 is optionally substituted heteroaryl; andn is 0, 1, 2, 3, or 4.