MATERIALS FORMABLE IN SITU WITHIN A MEDICAL DEVICE

摘要

Certain embodiments of the invention include forming a material in situ b y introducing into a space within a patient a water soluble polymer precurso r of at least about 10,000 molecular weight solubilized in a flowable aqueou s solution. Functional groups on the polymer precursor undergo covalent bond ing in situ to form a solid and nonbiodegradable material having a swellabil ity less than about 20% v/v and a Young's modulus of at least about 100 kPa within about 30 seconds to about 30 minutes of initiating a chemical reactio n of the functional groups to form the solid material.