发明名称 |
1.ALPHA.-HYDROXY-2-(3'-HYDROXYPROPYLIDENE)-19-NOR-VITAMIN D COMPOUNDS AND METHODS OF MAKING AND USE THEREOF. |
摘要 |
<p>Disclosed are 1alpha-hydroxy-2-(3'-hydroxypropylidene)-19-nor- vitamin D compounds, pharmaceutical compositions, and methods of making and treatment thereof. The compounds are generally directed to biologically active 2-alkylidene-19-nor-vitamin D compounds and analogs thereof characterized by the presence of a 3'-hydroxypropylidene moiety at C-2 and the presence of an abbreviated alkyl side-chain free of any hydroxyl moiety.</p> |
申请公布号 |
MX2008012701(A) |
申请公布日期 |
2009.01.07 |
申请号 |
MX20080012701 |
申请日期 |
2007.04.05 |
申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION. |
发明人 |
MARGARET CLAGETT-DAME;LORI A. PLUM;RAFAL R. SICINSKI;AGNIESZKA GLEBOCKA;HECTOR F. DELUCA |
分类号 |
C07C401/00;A61K31/59;A61P3/02;A61P35/00 |
主分类号 |
C07C401/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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