发明名称 |
COMPOSITION FOR PREVENTING AND TREATING CHOLESTEROL-RELATED DISEASES |
摘要 |
The present invention relates to a composition for preventing and treating cholesterol-related diseases and, more specifically, to a composition for preventing and treating cholesterol-related diseases, containing, as an active ingredient, a compound for inhibiting the linkage between PCSK9 and LDLR. The composition does not directly regulate the expression level of PCSK9 and/or LDLR in the liver, thereby lowering the resultant side effects; and effectively suppresses the linkage of PCSK9 and LDLR, thereby effectively lowering the total plasma cholesterol level and further increasing the therapeutic effect of a statin-based drug when administered in combination with the statin-based drug. |
申请公布号 |
WO2016108572(A2) |
申请公布日期 |
2016.07.07 |
申请号 |
WO2015KR14399 |
申请日期 |
2015.12.29 |
申请人 |
INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY |
发明人 |
PARK, SAHNG WOOK;LEE, HYUN SOOK;MIN, DONG KOOK;LEE, NA RAE;LEE, CHAN JOO;YANG, GA EUL |
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