发明名称 |
DISUBSTITUTED TRIFLUORMETHYLPYRIMIDINONES AND USE THEREOF AS CCR2 ANTAGONISTS |
摘要 |
The present application relates to novel 2,5-disubstituted 6-(trifluoromethyl)pyrimidin-4(3H)-one derivatives, to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases, and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for treatment and/or prevention of cardiovascular, renal, inflammatory and fibrotic diseases. |
申请公布号 |
EP3046912(A1) |
申请公布日期 |
2016.07.27 |
申请号 |
EP20140766967 |
申请日期 |
2014.09.12 |
申请人 |
BAYER PHARMA AKTIENGESELLSCHAFT |
发明人 |
STRAUB, ALEXANDER;COLLIN, MARIE-PIERRE;KOCH, MICHAEL;MEYER, JUTTA;SCHLEMMER, KARL-HEINZ;NISING, CARL FRIEDRICH;BIBER, NICOLE;ANLAUF, SONJA;WITTWER, MATTHIAS BEAT |
分类号 |
C07D239/56;A61K31/513;A61P9/00;A61P29/00;C07D239/36;C07D239/47;C07D239/54;C07D239/545 |
主分类号 |
C07D239/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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