发明名称 C-PHENYL GLYCITOL COMPOUND
摘要 Provided is a novel C-phenyl glycitol compound that may serve as a prophylactic or therapeutic agent for diabetes by inhibiting both SGLT1 activity and SGLT2 activity, thereby exhibiting a glucose absorption suppression action and a urine glucose excretion action. A C-phenyl glycitol compound represented by Formula (I) below or a pharmaceutically acceptable salt thereof or a hydrate thereof wherein R1 and R2 are the same or different and represent a hydrogen atom, a hydroxyl group, a C1-6 alkyl group, a C1-6 alkoxy group or a halogen atom, R3 is a hydrogen atom, a C1-6 alkyl group, a C1-6 alkoxy group or a halogen atom, Y is a C1-6 alkylene group, -O-(CH2)n- (n is an integer of 1 to 4) or a C2-6 alkenylene group, provided that when Z is -NHC(-NH)NH2 or -NHCON(RB)RC, n is not 1, Z is -CONHRA, -NHC(-NH)NH2 or -NHCON(RB)RC,
申请公布号 US2010022460(A1) 申请公布日期 2010.01.28
申请号 US20070301463 申请日期 2007.05.18
申请人 TAISHO PHARMACEUTICAL CO., LTD. 发明人 KAKINUMA HIROYUKI;KOBASHI YOHEI;HASHIMOTO YUKO;OI TAKAHIRO;TAKAHASHI HITOMI;AMADA HIDEAKI;IWATA YUKI
分类号 A61K31/70;C07H1/00 主分类号 A61K31/70
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