| 摘要 |
PROBLEM TO BE SOLVED: To provide a food composition and a pharmaceutical composition, which exhibit anti-obesity effects by means of a thermogenesis produced by an activity of an uncoupling protein (UCP) of fat cells, exhibit anti-diabetes effects by means of an improved insulin resistance, increase muscle mass, and improve capacity for exercise.SOLUTION: There are provided a novel use of a composition containing extracts of piper retrofractum; and a food composition or a pharmaceutical composition which exhibit anti-obesity effects by means of decreased body weight and body fat, exhibit anti-diabetes effects by means of ameliorated insulin resistance through the reduction of blood glucose and blood insulin, increase muscle mass by increasing an energy source being supplied to the muscles, and improve the capacity for exercise including increased endurance. An anti-obese pharmaceutical composition and a food composition which include a Piper retrofractum Vahl. fruit extract, as an active ingredient, obtained with an organic solvent or by supercritical extraction are also provided, where the active ingredient triggers a UCP activation-induced thermogenesis mechanism.SELECTED DRAWING: None |
