发明名称 THERAPEUTIC EFFECTS OF BRYOSTATINS, BRYOLOGS, AND OTHER RELATED SUBSTANCES ON ISCHEMIA/STROKE-INDUCED MEMORY IMPAIRMENT AND BRAIN INJURY
摘要 PROBLEM TO BE SOLVED: To provide pharmaceutical compositions that contains a protein-kinase-C (PKC) activator and a pharmaceutically acceptable carrier, and is useful for treating stroke.SOLUTION: The present invention provides a pharmaceutical composition selected from the group consisting of daphnane-type diterpene, bicyclic triterpenoid, diterpenoid, naphthalenesulfonamide, cis-unsaturated fatty acids, octylindolactam V, 2-[(2-pentylcyclopropyl)methyl] cyclopropaneoctanoic acid, 6-(2-(4-[(4-fluorophenyl)phenylmethylene]-1-piperidinyl)ethyl)-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one, [3-[2-[4-(bis-(4-fluorophenyl)methylene]piperidin-1-yl)ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone, or a combination thereof, as a PKC activator.SELECTED DRAWING: None
申请公布号 JP2016166207(A) 申请公布日期 2016.09.15
申请号 JP20160053863 申请日期 2016.03.17
申请人 BLANCHETTE ROCKEFELLER NEUROSCIENCES INST 发明人 MIAO-KUN SUN;ALKON DANIEL L
分类号 A61K31/11;A61K31/18;A61K31/19;A61K31/201;A61K31/216;A61K31/336;A61K31/407;A61K31/517;A61K31/519;A61P9/00;A61P43/00 主分类号 A61K31/11
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