| 发明名称 |
MODULATORS OF TNF- ALPHA SIGNALING |
| 摘要 |
<p>The present invention provides compounds which are modulators of TNF-.alpha. signaling and methods of use thereof for treating a patient having a TNF- .alpha. mediated condition. The compounds can be represented by structural formulas (I), (II) and (III).</p> |
| 申请公布号 |
CA2408408(A1) |
申请公布日期 |
2001.11.22 |
| 申请号 |
CA20012408408 |
申请日期 |
2001.05.10 |
| 申请人 |
GENZYME CORPORATION |
发明人 |
HIRTH, BRADFORD H.;NAHILL, SHARON R.;QIAO, SHUANG;VINICK, FRED;SNEDDON, SCOTT F.;KANE, JOHN L. |
| 分类号 |
C07D295/14;A61K31/277;A61K31/405;A61K31/417;A61K31/4178;A61K31/4439;A61K31/444;A61K31/498;A61K31/506;A61K31/53;A61K31/5375;A61K31/5377;A61P1/04;A61P1/16;A61P3/10;A61P5/14;A61P7/00;A61P7/02;A61P9/10;A61P9/14;A61P19/02;A61P21/04;A61P25/14;A61P25/28;A61P25/32;A61P29/00;A61P31/00;A61P31/04;A61P31/10;A61P31/12;A61P31/18;A61P33/00;A61P35/00;A61P35/02;A61P37/02;A61P37/06;A61P43/00;C07C255/60;C07D233/54;C07D233/64;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D405/12;C07D409/12;(IPC1-7):C07D233/54;C07D401/04;A61K31/395 |
主分类号 |
C07D295/14 |
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