发明名称 |
SYSTEMS, METHODS, AND COMPOSITIONS FOR CROSS-LINKING TREATMENTS OF AN EYE |
摘要 |
Systems, methods, and compositions generate cross-linking activity for treatment of eye disorders. Various agents, additives, buffers, etc., may be employed in formulations with a cross-linking agent to enhance treatment. For example, a composition for applying treatment to a cornea of an eye includes a cross-linking agent that generates cross-linking activity in the cornea in response to exposure to a photo-activating light. The composition also includes an iron additive and citrate buffer. In some cases, the cross-linking agent may include riboflavin. In other cases, the iron additive may include FeSO4. In further cases, the iron additive may be dissolved in the citrate buffer. |
申请公布号 |
WO2016090016(A1) |
申请公布日期 |
2016.06.09 |
申请号 |
WO2015US63466 |
申请日期 |
2015.12.02 |
申请人 |
AVEDRO, INC. |
发明人 |
KAMAEV, PAVEL;FRIEDMAN, MARC;SHERR, EVAN;PETERSON, SARAH, M.;MULLER, DAVID |
分类号 |
A61K31/525;A61K33/26;A61K41/00;A61P27/02 |
主分类号 |
A61K31/525 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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