发明名称 Novel diterpene compounds
摘要 The present invention provides a novel diterpene compounds with antineoplastic activities. The novel diterpene compounds of the present invention are represented by the general formula (I). R1 to R6 in the formula represent an aliphatic group, or a radical represented by the general formula RCO-, wherein R represents an aliphatic, an aromatic or a heteroaromatic group. The compounds of the present invention may be prepared by extracting roots of Euphorbia kansui L. with an organic solvent such as chloroform, ethyl acetate and butanol. These extracted compounds may be used as starting materials for the preparation of the compounds represented by the general formula (I). The compounds of the present invention have antineoplastic activities, and therefore, useful as antineoplastic agents.
申请公布号 US2005043549(A1) 申请公布日期 2005.02.24
申请号 US20040767436 申请日期 2004.01.30
申请人 NIHON UNIVERSITY 发明人 KITANAKA SUSUMU;MIYATA SYOHEI;WANG LIYAN;WANG NAILI;YAO XINSHENG
分类号 C07D493/08;A61K31/34;A61P35/00;C07D493/04;(IPC1-7):C07D493/04 主分类号 C07D493/08
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