IDENTIFICATION OF VARIANTS IN HISTONE DEACETYLASE 1 (HDAC1) TO PREDICT DRUG RESPONSE
摘要
Four previously unidentified missense mutations (M51L, Q111K, T114A and V157G) and a truncation mutation (R34Term) were identified in the HDAC1 genes of acute myeloid leukemia (AML) patients.
申请公布号
WO2006060429(A3)
申请公布日期
2006.10.05
申请号
WO2005US43198
申请日期
2005.11.30
申请人
NOVARTIS AG;NOVARTIS PHARMA GMBH;CULVER, KENNETH, WAYNE;ZHU, JIAN;LILLEBERG, STAN