发明名称 |
NOVEL N- (4- (AZETIDINE - 1 - CARBONYL) PHENYL) - (HETERO - ) ARYLSULFONAMIDE DERIVATIVES AS PYRUVATE KINASE M2 (PMK2) MODULATORS M2(PMK2) N-(4-(-1-))-() |
摘要 |
Compounds of general Formula (I), and compositions comprising compounds of general formula I that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that modulate PKM2 in the treatment of cancer. |
申请公布号 |
HK1190405(A1) |
申请公布日期 |
2016.12.02 |
申请号 |
HK20140103672 |
申请日期 |
2014.04.16 |
申请人 |
Agios Pharmaceuticals Inc. |
发明人 |
SALITURO, Francesco G. FG;SAUNDERS, Jeffrey O. JO;YAN, Shunqi |
分类号 |
C07D;A61K;A61P |
主分类号 |
C07D |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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