发明名称 NOVEL N- (4- (AZETIDINE - 1 - CARBONYL) PHENYL) - (HETERO - ) ARYLSULFONAMIDE DERIVATIVES AS PYRUVATE KINASE M2 (PMK2) MODULATORS M2(PMK2) N-(4-(-1-))-()
摘要 Compounds of general Formula (I), and compositions comprising compounds of general formula I that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that modulate PKM2 in the treatment of cancer.
申请公布号 HK1190405(A1) 申请公布日期 2016.12.02
申请号 HK20140103672 申请日期 2014.04.16
申请人 Agios Pharmaceuticals Inc. 发明人 SALITURO, Francesco G. FG;SAUNDERS, Jeffrey O. JO;YAN, Shunqi
分类号 C07D;A61K;A61P 主分类号 C07D
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