| 发明名称 |
METHODS AND COMPOSITIONS FOR MODULATING ESTROGEN RECEPTOR MUTANTS. |
| 摘要 |
Described herein are methods and compositions for treating an ER-related disease condition characterized by a mutation in the ESR1 gene by administering an estrogen receptor modulator. Also described herein are methods of treating hormone resistant-estrogen receptor (ER) positive breast cancers characterized by a mutation in the ESR1 gene by administering an estrogen receptor modulator. |
| 申请公布号 |
MX2016011698(A) |
申请公布日期 |
2016.12.12 |
| 申请号 |
MX20160011698 |
申请日期 |
2015.03.12 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
Nicholas D. SMITH;Lori FRIEDMAN;Deepak SAMPATH;Jeffrey H. HAGER;Edna CHOW MANEVAL;Debasish F. ROYCHOWDHURY;James D. JOSEPH;Jing QIAN |
| 分类号 |
A61K31/397;A61K31/4025;A61K31/416;A61K31/4245;A61K31/428;A61K31/5375 |
主分类号 |
A61K31/397 |
| 代理机构 |
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