发明名称 |
CELLEVÆKSTFREMGANGSMÅDE OG FARMACEUTISK PRÆPARAT TIL VÆVSREPARATION OG -REGENERERING |
摘要 |
The present invention relates to a method for growing, rapidly and massively ex vivo, cells collected from a living subject to provide a safe and effective pharmaceutical preparation for biological tissue repair/regeneration. Specifically, the present invention relates to a method for growing cells in a sample collected from a living subject by culturing the cells in a medium containing allogeneic (including autogenic) serum. Preferably the allogeneic serum has been determined as being negative for a serum tumor marker and/or an infectious factors, and the amount of the anticoagulant (e.g., heparin, a heparin derivative, or a salt thereof) added to the collected sample is less than 5 U/mL with respect to the volume of the sample or the amount of the anticoagulant in the medium at the start of culture is less than 0.5 U/mL. The present invention further relates to use of the method. |
申请公布号 |
DK2194121(T3) |
申请公布日期 |
2016.12.12 |
申请号 |
DK20080830989T |
申请日期 |
2008.09.10 |
申请人 |
Sapporo Medical University |
发明人 |
HONMOU, Osamu;HOUKIN, Kiyohiro |
分类号 |
A61K35/28;A61K35/12;A61P9/10;A61P25/00;C12N5/07;C12N5/074;C12N5/0775;C12N5/0797 |
主分类号 |
A61K35/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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