发明名称 |
FCRN ANTIBODIES AND METHODS OF USE THEREOF |
摘要 |
The present invention features antibodies that have high binding affinity to human neonatal Fc receptor (FcRn). These anti-FcRn antibodies are useful, e.g., to promote clearance of autoantibodies in a subject, to suppress antigen presentation in a subject, to block an immune response, e.g., block an immune complex-based activation of the immune response in a subject, and to treat immunological diseases (e.g., autoimmune diseases) in a subject. |
申请公布号 |
WO2016123521(A2) |
申请公布日期 |
2016.08.04 |
申请号 |
WO2016US15720 |
申请日期 |
2016.01.29 |
申请人 |
MOMENTA PHARMACEUTICALS, INC. |
发明人 |
KEHRY, MARILYN;KING, DAVID, J.;LING, LEONA, E.;MEADOR, JAMES III;ROY, SUCHARITA;MANNING, ANTHONY |
分类号 |
A61K39/395;C07K16/28 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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