| 发明名称 |
PROCESS FOR THE PREPARATION OF BOSENTAN |
| 摘要 |
The invention concerns a new process for the preparation of bosentan or bosentan monohydrate by reaction of compound of Formula II with ethylene glycol in the presence of potassium bases and the potassium salt of bosentan. |
| 申请公布号 |
EP2406235(B1) |
申请公布日期 |
2016.08.10 |
| 申请号 |
EP20100727818 |
申请日期 |
2010.03.03 |
| 申请人 |
SIFAVITOR S.R.L. |
发明人 |
BIFFI, GIANCARLO;FELICIANI, LAZZARO;VISCARDI, ENRICO |
| 分类号 |
C07D239/52;A61K31/513;A61P11/00 |
主分类号 |
C07D239/52 |
| 代理机构 |
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代理人 |
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