PHYSICS-BASED HIGH-RESOLUTION HEAD AND NECK BIOMECHANICAL MODELS

摘要

Systems and methods are shown for developing physics-based high resolution biomechanical head and neck deformable models for generating ground-truth deformations that can be used for validating both image registration and adaptive RT frameworks.

主权项

1. An apparatus for deformable image registration (DIR) of a target anatomy, the apparatus comprising:
(a) a computer processor; and (b) a non-transitory computer-readable memory storing instructions executable by the computer processor; (c) wherein said instructions, when executed by the computer processor, perform steps comprising:
(i) generating a high-resolution deformable biomechanical model from CT data acquired from a plurality of patient CT images of the target anatomy;(ii) simulating one or more deformations within said biomechanical model, the one or more deformations representing a range of inter-fraction patient posture changes and physiological regression; and(iii) generating modified CT images representing a deformed state of the target anatomy.