| 摘要 |
A manifold assembly has a manifold and can be located between a block and a plate, and serve as a stator for a valve or other component. The manifold, block or plate can have a plurality of ports either integral thereto or removably connected thereto, with the ports adapted to receive and sealingly engage with a tube having an inner tube layer, an outer tube layer, a sleeve, a tip portion, and a nut. Each of the nut, sleeve, inner and outer tubing layers, and tip portion have a passageway therethrough, with at least the passageways in the sleeve, tip portion, outer tube layer, and nut adapted to allow the inner tube layer to pass therethrough or extend over the inner layer. The ends of the tip portion and inner layer together can define a substantially flat surface which can form a seal in a flat-bottomed port of the manifold, block, or plate, which can be used in a component in an analytical instrument system, including for example a liquid chromatography system. The nut, tube, ferrule, and transfer tube or liner tube may comprise biocompatible materials. In addition, the nut may have a slot, such as a slot adapted to allow the tube and the nut to be easily and quickly separated or to allow a portion of the tube to be easily and quickly inserted in the nut. |
| 主权项 |
1. A manifold assembly comprising:
at least one nut having a passageway therethrough and having a first end and a second end; a block adapted to removably hold a manifold and having a plurality of ports therein, wherein each of the ports are adapted to removably and sealingly engage with said nut and an end of a tube; a manifold having a plurality of inlet ports therein, wherein at least a portion of said manifold is attached to said block, and wherein each of the ports of said block is in fluid communication with one of the inlet ports of said manifold; a tube having a passageway therethrough and adapted to fit in a passageway extending through said nut, wherein said tube has a first end and a second end; a transfer tube having a passageway therethrough, wherein at least a portion of said tube is located within the passageway of said transfer tube and is secured relative to said transfer tube; and a tip having a passageway therethrough and providing an interior portion, wherein said tip is adjacent to and in contact with one of the first end and the second end of said tube, wherein said tip is adapted to receive and hold a portion of one of the first end and the second end of said tube in the interior portion, wherein at least a portion of one end of the tip is adapted to form a seal in a port in fluid communication with said manifold, and wherein a portion of the tip is located between a portion of said tube and a portion of said transfer tube. |
