发明名称 |
ANTIBODY BINDING TO FCRN FOR TREATING AUTOIMMUNE DISEASES |
摘要 |
The present disclosure relates to an isolated anti-FcRn antibody, which is an antibody binding to FcRn (stands for neonatal Fc receptor, also called FcRP, FcRB or Brambell receptor) that is a receptor with a high affinity for IgG or a fragment thereof, a method of preparing thereof, a composition for treating autoimmune disease, which comprises the antibody, and a method of treating and diagnosing autoimmune diseases using the antibody. The FcRn-specific antibody according to the present disclosure binds to FcRn non-competitively with IgG to reduce serum pathogenic auto-antibody levels, and thus can be used for the treatment of autoimmune diseases. |
申请公布号 |
SG11201608208V(A) |
申请公布日期 |
2016.11.29 |
申请号 |
SG11201608208V |
申请日期 |
2015.04.30 |
申请人 |
HANALL BIOPHARMA CO., LTD. |
发明人 |
KIM, SUNG WUK;PARK, SEUNG KOOK;JEONG, JAE KAP;AHN, HYEA KYUNG;KIM, MIN SUN;KIM, EUN SUN;YONG, HAE-YOUNG;SHIN, DONGOK;SONG, YEON JUNG;YOO, TAE HYOUNG |
分类号 |
C07K16/46;A61K39/395;A61P37/00;C07K16/18;C12N15/13;C12N15/63;G01N33/53 |
主分类号 |
C07K16/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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