| 发明名称 |
CHIMERIC ANTIGEN RECEPTOR AND METHODS OF USE THEREOF |
| 摘要 |
The present disclosure provides a heterodimeric, conditionally active chimeric antigen receptor (CAR), and a nucleic acid comprising a nucleotide sequence encoding the CAR. The present disclosure provides cells genetically modified to produce the CAR. A CAR of the present disclosure can be used in various methods, which are also provided. |
| 申请公布号 |
EP2956175(A4) |
申请公布日期 |
2016.08.24 |
| 申请号 |
EP20140751227 |
申请日期 |
2014.02.14 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
WU, CHIA-YUNG;ONUFFER, JAMES;LIM, WENDELL A. |
| 分类号 |
A61K48/00;A61K35/17;A61K39/00;A61K47/48;C07K14/705;C07K14/725;C07K16/18;C07K16/28;C12N5/0783;C12N9/14;C12N9/90 |
主分类号 |
A61K48/00 |
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