METHODS OF STRATIFYING PATIENTS FOR TREATMENT WITH RETINOIC ACID RECEPTOR-α AGONISTS
摘要
The invention provides methods that define cellular populations that are sensitive to RARA agonists and identify patient subgroups that will benefit from treatment with RARA agonists. The invention also provides packaged pharmaceutical compositions that comprise a RARA agonist and instructions for determining if such agonist is suitable for use in treatment.
申请公布号
WO2016161107(A1)
申请公布日期
2016.10.06
申请号
WO2016US25256
申请日期
2016.03.31
申请人
SYROS PHARMACEUTICALS, INC.
发明人
CHEN, Mei Wei;COLLINS, Cindy;EATON, Matthew Lucas;GUENTHER, Matthew G.;KE, Nan;LOPEZ, Jeremy;MCKEOWN, Michael R.;ORLANDO, David A.