发明名称 |
2-(3-substituted-aryl)amino-4-aryl-thiazoles as tyrosine kinase inhibitors |
摘要 |
The present invention relates to novel compounds selected from 2-(3substitutedaryl)amino-4-aryl-thiazoles that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant tyrosine kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. More particularly, these compounds are potent and selective c-kit inhibitors. |
申请公布号 |
ZA200606152(B) |
申请公布日期 |
2007.11.28 |
申请号 |
ZA20060006152 |
申请日期 |
2006.07.25 |
申请人 |
AB SCIENCE |
发明人 |
MOUSSY, ALAIN;CIUFOLINI, MARCO;WERMUTH, CAMILLE;GIELTHEN, BRUNO |
分类号 |
A61K;C07D;C07D417/04;C07D417/14 |
主分类号 |
A61K |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|