| 发明名称 |
SMALL MOLECULE INHIBITORS OF EGFR AND PI3K |
| 摘要 |
This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a quinazoline structure or a quinoline structure which function as dual inhibitors of EGFR proteins and PI3K proteins, and their use as therapeutics for the treatment of cancer and other diseases. |
| 申请公布号 |
WO2016100347(A2) |
申请公布日期 |
2016.06.23 |
| 申请号 |
WO2015US65827 |
申请日期 |
2015.12.15 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
WHITEHEAD, CHRISTOPHER EMIL;LEOPOLD, JUDITH S. |
| 分类号 |
A61K31/5377;A61K31/517 |
主分类号 |
A61K31/5377 |
| 代理机构 |
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