摘要 |
The present invention relates to the methods for preparing brexpiprazole, the analogs, key intermediates, and salts thereof, specifically, the present invention relates to a new method for preparing brexpiprazole, the analogs, key intermediates, and salts thereof, and the key intermediates, and salts thereof provided during the preparation. The preparation method has a mild reaction condition, stable intermediate, easy operation, and uses cheap and easy-to-get reagents, thus it saves the synthesis cost, shortens the production cycle, improves the yield and product quality, and is suitable for mass production. |
申请人 |
SUZHOU VIGONVITA LIFE SCIENCES CO. LTD.;TOPHARMAN SHANGHAI CO., LTD.;SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES |
发明人 |
LIU, ZHENG;WU, CHUNHUI;LIU, YONGJIAN;ZHANG, RONGXIA;HE, YANG;TIAN, GUANGHUI;SHEN, JINGSHAN |