IONTOPHORETIC SYSTEM FOR TRANSDERMAL DELIVERY OF ACTIVE AGENTS FOR THERAPEUTIC AND MEDICINAL PURPOSES

摘要

An embodiment of a system includes a power source and at least two electrode assembles. The power source that an output current that alternates between a maximum current value and a minimum current value; a pair of electrode assemblies. Each electrode assembly is configured to be held in contact with a skin layer of a user. Additionally, each electrode assembly includes an electrode that is coupled to the power source to receive the output current from the power source. At least one of the electrode assemblies in the pair includes a medium that carries an active agent having a charge, the medium being provided on the at least one electrode assembly to enable the output current to repel the active agent into the skin layer for a duration in which the output current has a polarity that is the same as a polarity of the active agent.

主权项

1. A system for transdermal delivery of active agents for therapeutic and medicinal purposes, the system comprising:
a power source that generates a charged balanced alternating output current that varies between a first current value and a second current value; a pair of electrode assemblies comprising a first electrode assembly and a second electrode assembly, each electrode assembly applied to a corresponding skin layer of a user, and wherein each electrode assembly includes an electrode that is coupled to the power source to receive the output current; and wherein at least one of the electrode assemblies in the pair includes a contact thickness configured to carry an active agent having a charge, the contact thickness being provided on the at least one electrode assembly to enable the corresponding received output current to alternatively repel the active agent into the skin layer from the at least one electrode assembly for a duration in which the output current has a polarity that is the same as a polarity of the active agent, wherein the output current is generated according to a waveform in which the output current has the polarity that is the same as the polarity of the active agent is longer than a duration when a minimum value of the output current is zero or negative.