发明名称 NEW MULTI-THERAPY ADMINISTRATION PATTERNS SUITABLE FOR TREATING PERSONS AFFECTED BY HUMAN IMMUNODEFICIENCY VIRUS (HIV)
摘要 Pharmaceutical composition comprises three or four active ingredients comprising: a nucleoside reverse transcriptase inhibitor (NRTI) comprising emtricitabine and lamivudine; another nucleoside or nucleotide reverse transcriptase inhibitor (NRTI) comprising didanosine, abacavir and tenofovir; and the combination of ritonavir with protease inhibitor (PI) comprising lopinavir, fosamprenavir, atazanavir and darunavir, or a non nucleoside reverse transcriptase inhibitors (NNRTI) comprising efavirenz and etravirine, for a daily administration of one to four days per week to the human. An independent claim is included for a pharmaceutical product containing the nucleoside reverse transcriptase inhibitor comprising lamivudine and emtricitabine; another nucleoside or nucleotide reverse transcriptase inhibitor (NRTI) comprising didanosine, abacavir and tenofovir, and the combination of ritonavir with protease inhibitor comprising lopinavir, fosamprenavir, atazanavir and darunavir, or a non nucleoside reverse transcriptase inhibitors comprising efavirenz and etravirine, as a combination product for daily simultaneous, separate or staggered administration for one to four days per week in the treatment of HIV in humans. ACTIVITY : Anti-HIV. MECHANISM OF ACTION : Nucleoside reverse transcriptase inhibitor.
申请公布号 EP3067052(A3) 申请公布日期 2016.10.19
申请号 EP20160152625 申请日期 2010.11.19
申请人 ASSISTANCE PUBLIQUE-HÔPITAUX DE PARIS (APHP);UNIVERSITÉ DE VERSAILLES SAINT-QUENTIN-EN-YVELINES 发明人 LEIBOWITCH, JACQUES
分类号 A61K31/34;A61K31/426;A61K31/4418;A61K31/505;A61K31/513;A61K31/52;A61K31/536;A61K31/661;A61K31/675;A61K31/7068;A61P31/18 主分类号 A61K31/34
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