发明名称 THERAPEUTIC USES OF MICROVESICLES AND RELATED MICRORNAS
摘要 The present invention provides improved methods and compositions based on microvesicles for the treatment of various diseases, disorders and conditions. In particular, the present invention encompasses the recognition that microvesicles contain specific microRNAs which may function as intercellular regulators involved in cell or tissue regeneration, remodeling, reconstruction, reprogramming or transdifferentiation. Thus, among other things, the present invention provides methods and compositions based on microvesicles and/or associated microRNAs that provide more predictable and effective therapeutic results.
申请公布号 US2016243171(A1) 申请公布日期 2016.08.25
申请号 US201614987931 申请日期 2016.01.05
申请人 The University Court of the University of Glasgow 发明人 Shiels Paul;Davies Wayne
分类号 A61K35/407;C12N15/113;A61K35/28;A61K35/14;A61K9/50;A61K35/22 主分类号 A61K35/407
代理机构 代理人
主权项 1. A composition comprising purified microvesicles isolated from cells originated from kidney, liver, spleen, lymph node, myometrium, peripheral blood, cord blood, bone marrow, serum, mesenchymal tissue, or a combination thereof.
地址 Glasgow GB