| 发明名称 |
INHIBITORS OF PYRUVATE KINASE AND METHODS OF TREATING DISEASE |
| 摘要 |
The invention provides pharmaceutical compositions, kits, and methods of treating cancer, diabetes, obesity, autoimmune disease, and benign prostatic hyperplasia using compounds that selectively inhibit pyruvate kinase M2 and an assay measuring chemical modulation of pyruvate kinase activity. |
| 申请公布号 |
EP2054058(B1) |
申请公布日期 |
2016.11.09 |
| 申请号 |
EP20070836571 |
申请日期 |
2007.08.06 |
| 申请人 |
BETH ISRAEL DEACONESS MEDICAL CENTER |
发明人 |
CANTLEY, LEWIS, C.;VANDER HEIDEN, MATTHEW, G.;CHRISTOFK, HEATHER, R. |
| 分类号 |
A61K31/4184;A61K31/00;A61K31/381;A61K31/402;A61K31/426;A61P3/00;A61P3/10;A61P35/00;A61P37/00 |
主分类号 |
A61K31/4184 |
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