| 摘要 |
Disclosed herein are controlled-release formulations which exhibit substantially zero-order release kinetics. The formulations include a core comprising a core active agent and a wax excipient substantially coated with an extended-release coating. The formulation optionally includes an immediate-release portion comprising an immediate-release active agent in the form of, for example, a coating disposed on at least a portion of the core. Further disclosed are fexofenadine/pseudoephedrine combination formulations, which exhibit substantially no food effect. |
