| 摘要 |
There is disclosed a method of generating an animal model exhibiting an age-related pathological condition of the brain,the methodcomprising orally administering to the animal galactose and sodium benzoate. Also described is an animal model produced by this method. Further, a method of identifying a compound for the treatment of age-related pathological conditions of the brain is disclosed, the method comprising administering a candidate compound to a test animal model and detecting a change in an age-related pathological condition of the brain in the test animal model relative to a control. |
