发明名称 |
REDUCTION IN DEALLYLATION OF NALOXONE DURING STORAGE OF A SUSTAINED-RELEASE FORMULATION CONTAINING NALOXONE |
摘要 |
The present invention relates to: a packaged drug comprising a pharmaceutical sustained-release formulation of naloxone or of a pharmaceutically acceptable salt thereof and a packaging; a method for producing a drug with high storage stability, the method comprising the packaging of a sustained-release formulation of naloxone or of a pharmaceutically acceptable salt thereof; the use of a packaging for stabilising the storage of a drug comprising a pharmaceutical sustained-release formulation of naloxone or of a pharmaceutically acceptable salt thereof; and also the use of a packaging for reducing the deallylation of naloxone or of the pharmaceutically acceptable salt thereof during the storage of a pharmaceutical sustained-release formulation of naloxone or of a pharmaceutically acceptable salt thereof. |
申请公布号 |
WO2016203061(A1) |
申请公布日期 |
2016.12.22 |
申请号 |
WO2016EP70719 |
申请日期 |
2016.09.02 |
申请人 |
ACINO PHARMA AG |
发明人 |
KUBECEK, Jiri;NEUER, Klaus;ANDRES, Andrea |
分类号 |
A61K9/20;A61J1/00;A61K9/28;A61K31/00 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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