发明名称 EXTERNAL PREPARATION FOR SKIN
摘要 <p>Disclosed is an external preparation for the skin, which comprises a phospholipid having an iodine value of 80 to 110, ethanol in an amount of 55 to 83 wt% and water in an amount of 15 to 43 wt%, and which is improved in preparation stability by suppressing the increase in an acid value of the phospholipid. Also disclosed is an external preparation to the skin, which is improved in the transdermal absorption of a pharmacologically active ingredient contained therein. Further disclosed are: a method for suppressing the increase in an acid value of a phospholipid by employing a constitution comprising a phospholipid having a high iodine value, ethanol at a high concentration and water; and a method for improving the transdermal absorption of a pharmacologically active ingredient contained in an external preparation for the skin.</p>
申请公布号 WO2008047680(A1) 申请公布日期 2008.04.24
申请号 WO2007JP69860 申请日期 2007.10.11
申请人 ROHTO PHARMACEUTICAL CO., LTD.;ABE, MASAMICHI;HARADA, AYAKO;HONMA, YOICHI 发明人 ABE, MASAMICHI;HARADA, AYAKO;HONMA, YOICHI
分类号 A61K8/34;A61K47/02;A61K8/55;A61K47/10;A61K47/24;A61P17/04;A61P17/14;A61P29/00;A61P31/10;A61Q7/00 主分类号 A61K8/34
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