| 发明名称 |
Intranasal Administration of Ketamine to Treat Depression |
| 摘要 |
Methods and compositions for the treatment of treatment-resistant depression are described. More specifically, the invention demonstrates that intranasal administration of ketamine is effective to ameliorate the symptoms of depression in a patient who has not responded to an adequate trial of one antidepressant in the current episode and has recurrent or chronic depressive symptoms (>2 years).
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| 申请公布号 |
US2007287753(A1) |
申请公布日期 |
2007.12.13 |
| 申请号 |
US20070688603 |
申请日期 |
2007.03.20 |
| 申请人 |
MOUNT SINAI SCHOOL OF MEDICINE;NATIONAL INSTITUTE OF HEALTH;YALE UNIVERSITY SCHOOL OF MEDICINE |
发明人 |
CHARNEY DENNIS S.;MATHEW SANJAY J.;MANJI HUSSEINI K.;ZARATE CARLOS A.JR.;KRYSTAL JOHN H. |
| 分类号 |
A61K31/135;A61K33/14;A61K36/00;A61M5/00;A61M11/00;A61P25/24 |
主分类号 |
A61K31/135 |
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