发明名称 4-Phenyl-Pyrimidine-2-Carbonitrile Derivatives
摘要 The invention relates to 4-phenyl-pyrimidine-2-carbonitrile derivatives having the general formula I wherein each of the substituents is given the definition as set forth in the specification and claims, or a pharmaceutically acceptable salt thereof. The invention also relates to pharmaceutical compositions comprising the derivatives as well as to the use thereof in the treatment of osteoporosis, atherosclerosis, inflammation and immune disorders, such as rheumatoid arthritis, and chronic pain, such as neuropathic pain.
申请公布号 US2008090813(A1) 申请公布日期 2008.04.17
申请号 US20050628623 申请日期 2005.06.09
申请人 N.V. ORGANON 发明人 CAI JIAQIANG;RANKOVIC ZORAN;MOIR JENNIFER H.
分类号 A61K31/505;A61K31/506;A61K31/5377;A61K31/551;A61K31/5513;A61P9/10;A61P19/00;A61P29/00;A61P37/00;C07D239/28;C07D243/14;C07D401/02;C07D403/02;C07D413/02 主分类号 A61K31/505
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