BIOCOMPATIBLE IMPLANTS AND METHODS OF MAKING AND ATTACHING THE SAME
摘要
The invention provides a biocompatible silicone implant that can be securely affixed to living tissue through interaction with integral membrane proteins (integrins). A silicone article containing a laser-activated surface is utilized to make the implant. One example is an implantable prosthesis to treat blindness caused by outer retinal degenerative diseases. The device bypasses damaged photoreceptors and electrically stimulates the undamaged neurons of the retina. Electrical stimulation is achieved using a silicone microelectrode array (MEA). A safe, protein adhesive is used in attaching the MEA to the retinal surface and assist in alleviating focal pressure effects. Methods of making and attaching such implants are also provided.
申请公布号
WO2008143733(A3)
申请公布日期
2009.01.08
申请号
WO2008US02865
申请日期
2008.03.03
申请人
DOHNEY EYE INSTITUTE;ROWLEY, ADRIAN;LAUDE, LUCIEN;HUMAYUN, MARK;WEILAND, JAMES
发明人
ROWLEY, ADRIAN;LAUDE, LUCIEN;HUMAYUN, MARK;WEILAND, JAMES