发明名称 QUINAZOLINE ANALOGS AS RECEPTOR TYROSINE KINASE INHIBITORS
摘要 This invention provides quinazoline analogs of Formula (I): where A is bonde d to at least one of the carbons at the 5, 6, 7 or 8 position of the bicyclic ring, and the ring is substituted by up to two independent R3 groups. The invention also includes methods of using compounds of Formula (I) as type I receptor tyrosine kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
申请公布号 CA2535614(A1) 申请公布日期 2005.02.24
申请号 CA20042535614 申请日期 2004.08.10
申请人 ARRAY BIOPHARMA, INC. 发明人 ZHAO, QIAN;BUCKMELTER, ALEXANDRE;WALLACE, ELI;LYSSIKATOS, JOSEPH;TOPALOV, GEORGE
分类号 A61K31/51;A61K31/517;A61K31/535;C07D239/82;C07D239/94;C07D401/12;C07D403/00;C07D413/12;C07D413/14;C07D417/14;C07D498/04;C07D498/08 主分类号 A61K31/51
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