发明名称 |
QUINAZOLINE ANALOGS AS RECEPTOR TYROSINE KINASE INHIBITORS |
摘要 |
This invention provides quinazoline analogs of Formula (I): where A is bonde d to at least one of the carbons at the 5, 6, 7 or 8 position of the bicyclic ring, and the ring is substituted by up to two independent R3 groups. The invention also includes methods of using compounds of Formula (I) as type I receptor tyrosine kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
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申请公布号 |
CA2535614(A1) |
申请公布日期 |
2005.02.24 |
申请号 |
CA20042535614 |
申请日期 |
2004.08.10 |
申请人 |
ARRAY BIOPHARMA, INC. |
发明人 |
ZHAO, QIAN;BUCKMELTER, ALEXANDRE;WALLACE, ELI;LYSSIKATOS, JOSEPH;TOPALOV, GEORGE |
分类号 |
A61K31/51;A61K31/517;A61K31/535;C07D239/82;C07D239/94;C07D401/12;C07D403/00;C07D413/12;C07D413/14;C07D417/14;C07D498/04;C07D498/08 |
主分类号 |
A61K31/51 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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