Various systems and methods are implemented for controlling stimulus of a cell. One such method is implemented for optical stimulation of a cell expressing an NpHR ion pump. The method includes the step of providing a sequence of stimuli to the cell. Each stimulus increases the probability of depolarization events occurring in the cell. Light is provided to the cell to activate the expressed NpHR ion pump, thereby decreasing the probability of depolarization events occurring in the cell.
申请公布号
WO2008086470(A1)
申请公布日期
2008.07.17
申请号
WO2008US50745
申请日期
2008.01.10
申请人
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;ZHANG, FENG;DEISSEROTH, KARL;BOYDEN, EDWARD, STUART
发明人
ZHANG, FENG;DEISSEROTH, KARL;BOYDEN, EDWARD, STUART