Verfahren zum Nachweis eines Restanalyts in einer Probe
摘要
A test device for detecting the presence of a residue analyte in a sample includes a support strip and a sample-absorbing matrix attached to the support strip. The sample-absorbing matrix has a material for absorbing an amount of the sample. The test device also includes a mobile-phase support for holding a mobile-phase composition. The mobile-phase support is attached to the support strip and in contact with the sample-absorbing matrix. A mobile-phase composition is disposed on the mobile-phase support and has a receptor for binding with the analyte. The mobile-phase composition can be carried in the sample. A stationary-phase membrane is attached to the support strip and has a first membrane end in contact with the mobile-phase composition and a second membrane end. The membrane allows lateral capillary flow of the sample from the first membrane end to the second membrane end. A test zone is on the stationary-phase membrane between the first membrane end and second membrane end and having a first binder for binding with an unbound receptor. A control zone is the stationary-phase a membrane between the test zone and second membrane end and has a second binder for binding with an analyte-bound receptor or residual unbound receptor.
申请公布号
DE69840657(D1)
申请公布日期
2009.04.23
申请号
DE1998640657
申请日期
1998.07.16
申请人
CHARM SCIENCES INC.
发明人
MARKOVSKY, ROBERT J.;FRANCISCO, CHERYL A.;CHARM, STANLEY E.;DONAHUE, PAUL R.;AGI-GLICKMAN, YAEL;SAUL, STEVEN J.;SCHEEMAKER, JOAN L.;SKIFFINGTON, RICHARD T.;TRIVEDI, SHIFALI B.;ZOMER, ELIEZER