摘要 |
PROBLEM TO BE SOLVED: To provide a manufacturing method of erlotinib by simpler and cheaper processes than conventional method.SOLUTION: There is provided a manufacturing method of erlotinib including (a) a process of reacting a compound of the formula (II) and a compound of the formula (III) and (b) a process of treating by a source substance of hydrochloric acid in a suitable solvent to provide erlotinib hydrochloride.SELECTED DRAWING: None |