An autophagy-inducing compound comprises an autophagy-inducing peptide comprising beclin-1 residues 269-283 and a heterologous moiety that promotes therapeutic stability or delivery of the compound. The compound may be used to induce autophagy and in assays with beclin-1 binding partners.
申请公布号
EP2812347(B1)
申请公布日期
2016.08.24
申请号
EP20130746727
申请日期
2013.01.20
申请人
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM;BAYLOR COLLEGE OF MEDICINE
发明人
LEVINE, BETH C.;SHOJI-KAWATA, SANAE;LICHTARGE, OLIVIER;WILKINS, ANGELA D.
