发明名称 |
COMBINATION OF β-ADRENERGIC RECEPTOR ANTAGONISTS AND CHECK POINT INHIBITORS FOR IMPROVED EFFICACY AGAINST CANCER |
摘要 |
Provided are methods for prophylaxis and/or therapy of cancer that include administering to an individual in need thereof an effective amount of a β-blocker and an immune checkpoint inhibitor such that growth of cancer in the individual is inhibited. Patients include those diagnosed with or at risk for a wide variety of cancer types. Methods are provided for cancer treatment in individuals who are resistant to checkpoint inhibitor monotherapies. Greater than additive anti-cancer effects may be achieved. |
申请公布号 |
WO2016145427(A1) |
申请公布日期 |
2016.09.15 |
申请号 |
WO2016US22277 |
申请日期 |
2016.03.14 |
申请人 |
HEALTH RESEARCH, INC. |
发明人 |
REPASKY, Elizabeth;HYLANDER, Bonnie |
分类号 |
A61K38/17;A61K39/04;A61K39/395;C07K16/30 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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