发明名称 |
IMMUNIZING PEPTIDE, METHOD FOR PRODUCING IMMUNIZING PEPTIDE, PHARMACEUTICAL COMPOSITION FOR IMMUNE DISORDERS CONTAINING SAME, AND METHOD FOR TREATING IMMUNE DISORDERS |
摘要 |
Provided is a novel immunizing peptide with which it is possible to induce antibody production to complexes that include the immunizing peptide and the MHC molecule of a living body. The immunizing peptide of the present invention is characterized in that: the immunizing peptide includes a T-cell epitope and antibody induction portion of a target protein; the antibody induction portion comprises one or more consecutive amino acids sequences upstream from the N-end amino acid of the T-cell epitope, and/or one or more consecutive amino acids sequences downstream from the C-end amino acid of the T-cell epitope, in the amino acid sequence of the target protein; and, when administered to a living body, the immunizing peptide induces antibody production to complexes that include the immunizing peptide and the MHC molecule of the living body. |
申请公布号 |
WO2016159181(A1) |
申请公布日期 |
2016.10.06 |
申请号 |
WO2016JP60556 |
申请日期 |
2016.03.30 |
申请人 |
OSAKA UNIVERSITY |
发明人 |
ARASE Hisashi;KISHIDA Kazuki |
分类号 |
C07K19/00;A61K38/00;A61P37/04;A61P37/06;A61P37/08;C07K14/47;C07K14/74;C12N15/09 |
主分类号 |
C07K19/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|