The invention relates to a new laccase from rumen, namely the RL5 laccase. In particular, the invention relates to a polypeptide comprising the amino acid sequence shown in Figure 9 and comprising at least the amino acids No. 80 to No. 150 of the amino acid sequence shown in Figure 9, respectively. The invention also relates to the use of polypeptides further comprising the amino acid sequence of a DUF152 domain with a core sequence as shown in Figure 16 as laccases. Furthermore, the invention relates to methods for producing inventive polypeptides and their use.
