发明名称 |
PYRIDINE COMPOUNDS AND METHODS OF THEIR USE |
摘要 |
Novel pyridine compounds, pharmaceutical compositions containing the pyridine compounds, and methods of their pharmaceutical use are disclosed. In certain embodiments, the pyridine compounds are agonists and/or ligands of cannabinoid receptors and may be useful, inter alia, for treating and/or preventing pain, gastrointestinal disorders, inflammation, auto-immune diseases, ischemic conditions, immune-related disorders, hypertension, neurological disorders, and neurodegenerative diseases, for providing cardioprotection against ischemic and reperfusion effects, for inducing apoptosis in malignant cells, for inhibiting mechanical hyperalgesia associated with nerve injury, and as an appetite stimulant. |
申请公布号 |
WO2008063625(A3) |
申请公布日期 |
2008.07.17 |
申请号 |
WO2007US24220 |
申请日期 |
2007.11.19 |
申请人 |
ADOLOR CORPORATION;DOLLE, ROLAND, E.;WORM, KARIN;GOODMAN, ALLAN, J.;CHU, GUO-HUA;LEBOURDONNEC, BERTRAND |
发明人 |
DOLLE, ROLAND, E.;WORM, KARIN;GOODMAN, ALLAN, J.;CHU, GUO-HUA;LEBOURDONNEC, BERTRAND |
分类号 |
C07D401/06;A61K31/42;A61P25/00;C07D413/06;C07D413/14;C07D417/06 |
主分类号 |
C07D401/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|