发明名称 |
IDENTIFICATION OF JAK/STAT PATHWAY MODULATING GENES BY GENOME WIDE RNAI SCREENING |
摘要 |
<p>The present invention relates to a method for identifying a compound capable of modulating the activity of the JAK/STAT pathway and to the use of different JAK/STAT pathway components as a target for the modulation of the activity of the JAK/STAT pathway. Moreover, the present invention is concerned with a method for modulating the activity of the JAK/STAT pathway. Furthermore, the present invention pertains to a pharmaceutical composition and to the use of different JAK/STAT pathway components and/or effector molecules thereof for the manufacture of such composition for the diagnosis, prevention or treatment of a JAK/STAT pathway associated disorder.</p> |
申请公布号 |
EP1910539(A2) |
申请公布日期 |
2008.04.16 |
申请号 |
EP20060762050 |
申请日期 |
2006.06.14 |
申请人 |
DEUTSCHES KREBSFORSCHUNGSZENTRUM, STIFTUNG DES OEFFENTLICHEN RECHTS;MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. |
发明人 |
BOUTROS, MICHAEL;ZEIDLER, MARTIN;MUELLER, PATRICK |
分类号 |
C12N15/11;A61K31/713;A61K38/17;C07K14/47;C12N15/113;C12Q1/68;G01N33/68 |
主分类号 |
C12N15/11 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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