| 发明名称 |
SOLID PHARMACEUTICAL PREPARATION |
| 摘要 |
<p>The present invention provides a solid preparation containing an insulin sensitizer and an active ingredient (except insulin sensitizers), which shows in vivo dissolution behavior of an insulin sensitizer, which is similar to the dissolution behavior of an insulin sensitizer from "a solid preparation containing an insulin sensitizer alone as an active ingredient". The present invention provides a solid preparation containing (1) a layer containing an insulin sensitizer, and (2) a layer containing (a) an active ingredient (except insulin sensitizers), (b) microcrystalline cellulose having a mean particle size of 5-25 µm, (c) microcrystalline cellulose having a mean particle size of 30-100 µm and (d) polyvinylpyrrolidone K-90.</p> |
| 申请公布号 |
EP1738754(A1) |
申请公布日期 |
2007.01.03 |
| 申请号 |
EP20050734290 |
申请日期 |
2005.04.13 |
| 申请人 |
TAKEDA PHARMACEUTICAL COMPANY LIMITED |
发明人 |
KOIKE, MASAHIKO;KOYAMA, HIROYOSHI;HAMAGUCHI, NAORU |
| 分类号 |
A61K31/155;A61K9/20;A61K9/24;A61K9/28;A61K9/32;A61K9/36;A61K31/4439;A61K45/06;A61K47/32;A61K47/38;A61P1/00;A61P1/02;A61P1/04;A61P1/12;A61P1/16;A61P1/18;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P5/50;A61P7/00;A61P7/02;A61P7/10;A61P9/00;A61P9/10;A61P9/12;A61P11/00;A61P13/02;A61P13/08;A61P13/10;A61P13/12;A61P15/08;A61P17/00;A61P19/02;A61P19/06;A61P19/08;A61P19/10;A61P21/04;A61P25/00;A61P25/02;A61P25/28 |
主分类号 |
A61K31/155 |
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